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Swiss Postpartum Hypertension Cohort
Sponsor: University Hospital, Basel, Switzerland
Summary
This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal risk. Current disease management strategies will be evaluated.
Official title: Swiss Postpartum Hypertension Cohort (Swiss-PPHT)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
480
Start Date
2020-06-04
Completion Date
2030-05
Last Updated
2025-05-28
Healthy Volunteers
No
Conditions
Interventions
Data collection for parameters of organ damage (cardiac and renal blood markers)
Blood results will be taken out of next routine venipuncture. Routinely collected standard parameters are a blood count, chemistry panel including renal parameters and electrolytes, lipid profile and a HbA1c as well as albumin/creatinine and protein/creatinine ratio in urine.
Data collection for blood pressure (BP)
Clinic blood pressure and 24hour BP Measurements
Home-based blood pressure management (substudy)
Subjects participating in home-based blood pressure management via telemonitoring will receive a free HekaHealth application (App) for the structured assessment of HBPM.
Biomarker Profiles (substudy)
Substudy where possible cardiac, renal and pregnancy related biomarkers will be additionally analyzed. The following biomarkers will be analyzed: N terminal (NT)-proBNP, Troponin, elevated mid-regional pro-atrial natriuretic peptide (ANP), elevated mid-regional pro adrenomedullin (ADM), soluble fms-like tyrosine kinase (sFlt-1), and placenta growth factor (PlGF).
Data collection on patient reported outcomes
Data collection on patient reported outcomes (Questionnaire EQ-5D, Questionnaire for App based monitoring )
Locations (1)
Medical Outpatient Department and Hypertension Clinic, University Hospital Basel
Basel, Switzerland