Clinical Research Directory

Inclusion Criteria: * Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005 * Age between ≥ 18 and ≤ 65 years old * Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test * Have not had a definite relapse for at least 6 weeks * Be at least 4 weeks away from a corticosteroid bolus * Lack of neuroleptic treatment * Patient with an Internet connection * Signed informed consent Exclusion Criteria: * Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment. * Neuropsychological care * Inability to receive oral and written information * Inability to use the software (due in particular to motor and / or sensory difficulties), * Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome * Patient with severe anxiodepressive syndrome (BDI\> 27) * Participation in an interventional study on cognitive functions * Patient under legal protection, guardianship or curatorship * Pregnant or breastfeeding women