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Follow-up and Outcome of Operative Treatment With Decompressive Release Of The Peroneal Nerve
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
The FOOT DROP trial is a prospective, multi-center, randomized controlled trial to assess if decompressive surgery for peroneal nerve entrapment is superior to maximal conservative treatment. Patients with persisting foot drop due to peroneal nerve entrapment will be randomized to either surgery or conservative treatment if foot drop persists 10 +/- 4 weeks after onset of symptoms. Patients will be evaluated through several questionnaires, evolution of muscle strength and several types of gait assessments. Primary endpoint is the difference in distance covered during the six minute walking test between baseline and 9 months after randomization.
Official title: A Prospective, Multi-center, Randomized, Parallel-group Controlled Trial to Compare Conservative Versus Surgical Treatment of Foot Drop in Peroneal Nerve Entrapment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
182
Start Date
2021-04-28
Completion Date
2028-12-31
Last Updated
2024-07-01
Healthy Volunteers
No
Conditions
Interventions
Neurolysis peroneal nerve
The surgical approach for entrapment at the fibular head is usually through a curvilinear incision just distal to the fibular head. The subcutaneous tissue is bluntly dissected, and the common peroneal nerve is identified proximal to the peroneus longus muscle. The peroneal nerve is then released from the surrounding fibrous tissue and fascia. The nerve is decompressed distally as it dives under the peroneus longus muscle. The decompression at this site is essential. Certain authors state that an adequate decompression should extend beyond the bifurcation in the deep and superficial peroneal nerve and should involve cutting the intermuscular septa
Maximal physiotherapy
Mobilization of ankle and foot, stretching of the calf muscles (prevention of contractures) Tonification of the dorsiflexion- and eversion muscles of the ankle Proprioceptive training Gait rehabilitation Home exercise schedule
Locations (18)
AZ Sint-Maarten
Mechelen, Antwerpen, Belgium
AZ Turnhout
Turnhout, Antwerpen, Belgium
Sint Augustinus
Wilrijk, Antwerpen, Belgium
Jessa Ziekenhuis
Hasselt, Limburg, Belgium
AZ Vesalius
Tongeren, Limburg, Belgium
AZ Alma
Eeklo, Oost-Vlaanderen, Belgium
AZ Sint-Lucas
Ghent, Oost-Vlaanderen, Belgium
AZ Sint-Jan
Bruges, West-Vlaanderen, Belgium
AZ Groeninge, department of neurosurgery
Kortrijk, West-Vlaanderen, Belgium
AZ Damiaan
Ostend, West-Vlaanderen, Belgium
AZ Delta
Roeselare, West-Vlaanderen, Belgium
Universitaire Ziekenhuizen Antwerpen
Antwerp, Belgium
ULB Erasme, department of neurosurgery
Brussels, Belgium
UZ Brussel
Brussels, Belgium
Ziekenhuis Oost-Limburg, department of neurosurgery
Genk, Belgium
University Hospitals Of Leuven, department of neurosurgery
Leuven, Belgium
CHU de Liège, department of neurosurgery
Liège, Belgium
Leids Universitair Medisch Centrum, department of neurosurgery
Leiden, Netherlands