Clinical Research Directory

Inclusion Criteria: * Patient over 18 years of age * Presenting with an ACS for which reperfusion therapy is indicated according to European and North American recommendations (IV thrombolysis or mechanical thrombectomy or a combination of both) * Having received informed information about the study and having signed a consent form to participate in the study (if this is not possible: information and consent from a trusted person or family member if present; emergency inclusion if absent) * Affiliated with or beneficiary of a social security system Exclusion Criteria: * Contraindication to performing a brain MRI (claustrophobia, pacemaker, or other implantable device contraindicating the performance of an MRI) * Intracranial hemorrhage associated with AIC on initial imaging Immunosuppressive treatment or corticosteroid therapy at patient admission * Pre-existing neurological disability limiting neurological assessment at 3 months (mRS\>2 at admission) * Known and diagnosed dementia pre-existing at the time of the AIC * Absolute or relative contraindication to the injection of gadolinium (history of true allergic reaction or intolerance to gadobutrol, renal failure with creatinine clearance \<15mL/min, pregnant or breastfeeding women) * Patient treated by another institution and referred solely for mechanical thrombectomy * Patient benefiting from legal protection measures