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3DUS Imaging of Needles in Gynecological Brachytherapy
Sponsor: Western University, Canada
Summary
Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue. Interstitial or intra-cavitary brachytherapy are often needed in advanced or recurrent disease, in cases where intrauterine brachytherapy may not deliver the optimal outcome. Interstitial or intra-cavitary brachytherapy are based on a defined template-and-needle system, and the procedure relies on clinical examination and pre-treatment imaging to guide needle insertion. There is currently no standard image-guided process to help direct needles in the pelvis. We propose using 3D ultrasound to provide real-time imaging for the brachytherapy procedure, which will aid in avoiding needle insertion into pelvic organs and result in optimal dose coverage to the tumour.
Official title: A Multi-Modality Comparison of Needle Placement During Gynecological Brachytherapy Procedures
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
35
Start Date
2022-10-15
Completion Date
2026-06
Last Updated
2025-04-13
Healthy Volunteers
No
Conditions
Interventions
Gynecological brachytherapy
Management of gynecological malignancies is done through brachytherapy treatment, which involves the delivery of radiation via radioactive sources that are placed into or in close proximity to the tumour.
Locations (1)
London Regional Cancer Program, Victoria Hospital
London, Ontario, Canada