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Efficacy and Safety of Fecal Microbiota Transplantation
Sponsor: Guangzhou First People's Hospital
Summary
In recent years, researches illustrate that multifactorial diseases such as functional gastrointestinal disorders, autoimmune diseases, metabolic, behavioral and neurological diseases are associated with an abnormal microbiome structure-dysbiosis, which means the imbalance of the microbiome community. Fecal microbiota transplantation (FMT), the infusion of faeces from a healthy donor to the gastrointestinal tract of a recipient patient aiming to alter the intestine microbiota, is recommended to be performed in Clostridium difficile infection(CDI) as the most effective therapy. It also being used experimentally in the treatment of the disease states linked to dysbiosis of the intestinal microbiota. However, the efficacy and safety of FMT to treat the dysbiosis-associated diseases is still in its infancy. To further verify the indications above, more data is required to be collected through studies.
Official title: Efficacy and Safety of Fecal Microbiota Transplantation in Patients With Intestinal Dysbiosis -A Pilot Study
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2021-01-15
Completion Date
2026-12-31
Last Updated
2021-04-08
Healthy Volunteers
No
Conditions
Interventions
Fecal Microbiota Transplantation
Procedure: Fecal Microbiota Transplantation
Locations (1)
Guangzhou First People's Hospital
Guangzhou, Guangdong, China