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Is Clonal Hematopoiesis of Indeterminate Potential Associated With Unprovoked Pulmonary Embolism?
Sponsor: Centre Hospitalier Universitaire, Amiens
Summary
The clonal hematopoiesis of indetermined prognosis (CHIP) has been described as risk factor for juvenile atherosclerosis. Moreover, some of CHIP genes are responsible of myeloproliferative disorders. Venous thrombosis are frequent in these disorders. The purpose of this project is to determine if CHIP is frequent in unprovoked pulmonary embolism and could be part of the pathophysiology.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
544
Start Date
2021-02-01
Completion Date
2026-01
Last Updated
2025-05-29
Healthy Volunteers
No
Conditions
Interventions
blood sample
Blood sample withdrawal in order to perform DNA sequencing
Locations (1)
CHU Amiens
Amiens, France