Clinical Research Directory
Browse clinical research sites, groups, and studies.
Fluorescent Intra-operative Tumor Margin Examination
Sponsor: Kurt Weiss
Summary
Tumor margin confirmation is important to confirming appropriate disease excision. Current standard of care is to take select margin samples to pathology for intra-operative readings. However, this is expensive, time consuming, and only assesses the margin contained within the specific sample. In prior work the investigators have determined that indocyanine green (ICG) is highly specific to the tumor bed when injected shortly before surgery. The investigators hypothesize that ICG will be able to accurately identify residual positive tumor margins during sarcoma excision procedures.
Official title: Evaluation of Intraoperative Tumor Margin Identification With Fluorescent Dye Imaging
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
110
Start Date
2021-03-02
Completion Date
2026-12-31
Last Updated
2026-02-20
Healthy Volunteers
No
Conditions
Interventions
Indocyanine green solution administered at 2.0mg/kg.
Dosing of ICG to be administered at 2.0mg/kg, two hours prior to surgery.
Stryker SPY-PHI Imaging Device
The SPY-PHI system is used with the ICG dye to provide fluorescence images.
Locations (1)
UPMC-Shadyside Hospital
Pittsburgh, Pennsylvania, United States