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RECRUITING
NCT04723888
NA

Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

Sponsor: RenJi Hospital

View on ClinicalTrials.gov

Summary

The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.

Official title: The Intervention Effect Of Alpha-Ketoglutarate On Abdominal Aortic Aneurysm Progression and Rupture: A Prospective, Randomized Parallel Controlled Study Based On Large Cohorts

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2021-02-01

Completion Date

2026-12-31

Last Updated

2021-02-21

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

alpha-ketoglutarate

alpha-ketoglutarate supplements

Locations (1)

Cardiology, Ren Ji Hospital

Shanghai, China