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Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture
Sponsor: RenJi Hospital
Summary
The objective of this project is to define whether nutritional supplement (oral administration with alpha-ketoglutarate) capable of filling-up the citric acid cycle (anaplerotic therapy) can improve outcomes in patients with an abdominal aortic aneurysm of 39-49 mm in diameter on ultrasound imaging. Alpha-ketoglutarate is commonly used as a nutritional supplement specially by athletes to increase muscle strength. They can be mixed with formula or other foods. Subjects will be followed for up to 5 years.
Official title: The Intervention Effect Of Alpha-Ketoglutarate On Abdominal Aortic Aneurysm Progression and Rupture: A Prospective, Randomized Parallel Controlled Study Based On Large Cohorts
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2021-02-01
Completion Date
2026-12-31
Last Updated
2021-02-21
Healthy Volunteers
No
Interventions
alpha-ketoglutarate
alpha-ketoglutarate supplements
Locations (1)
Cardiology, Ren Ji Hospital
Shanghai, China