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ACTIVE NOT RECRUITING
NCT04727788

Validation of Genomic Immune-phenotyping Profiles to Predict Risk of Kidney Transplant Rejection

Sponsor: Verici Dx

View on ClinicalTrials.gov

Summary

Global, non-randomized, observational study for the validation of Verici Dx genomic tests to predict risk of kidney clinical and subclinical acute rejection, and chronic allograft damage or interstitial fibrosis / tubular atrophy by correlating peripheral blood gene expression profiles with graft injury (e.g. cellular / antibody-mediated), rejection and death censored graft loss.

Official title: Validation of Genomic Immune-phenotyping Profiles in Peripheral Blood Gene Signatures to Predict Risk of Kidney Transplant Rejection

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

550

Start Date

2021-03-21

Completion Date

2025-12-31

Last Updated

2025-11-20

Healthy Volunteers

No

Locations (13)

University of Illinois at Chicago

Chicago, Illinois, United States

Northwestern University

Evanston, Illinois, United States

University of Maryland

Baltimore, Maryland, United States

Henry Ford

Detroit, Michigan, United States

University of Nebraska Medical Center

Omaha, Nebraska, United States

Cleveland Clinic

Cleveland, Ohio, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

University of Washington

Seattle, Washington, United States

CHU Grenoble Alpes Health Center

Grenoble, France

Bologna University

Bologna, Italy

Brescia University

Brescia, Italy

University Hospital Vall d'Hebron, Barcelona

Barcelona, Spain