Clinical Research Directory
Browse clinical research sites, groups, and studies.
AMBulatory UltraSound for Heart Failure Management
Sponsor: Central Hospital, Nancy, France
Summary
AMBUSH study is a multicenter randomized, controlled, open-label clinical trial (PROBE (Prospective Randomized Open Blinded End-point) type). The main objective of AMBUSH study is to assess the effect of therapeutic management guided by pulmonary ultrasound and the assessment of the inferior vena cava in patients with heart failure seen in an ambulatory (outpatient) setting on a mixed clinical-biological endpoint (including variations of natriuretic peptides - NtProBNP) at 30 days.
Official title: Impact of Ultrasound-guided Therapeutic Management of Ambulatory Patients With Heart Failure : An Open-label Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
182
Start Date
2023-05-15
Completion Date
2027-06-15
Last Updated
2023-05-17
Healthy Volunteers
No
Conditions
Interventions
An ultrasound (lung and inferior vena cava) will be performed and the heart failure treatments will be guided by the results of the lung ultrasound and the evaluation of the inferior vena cava.
An ultrasound (lung and inferior vena cava) will be performed and the heart failure treatments will be guided by the results of the lung ultrasound and the evaluation of the inferior vena cava. The choice of congestion treatment modalities to be implemented is left to the investigators' discretion, in accordance with European practice guidelines.
Usual care without ultrasound guidance
Usual care (i.e. without ultrasound guidance)
Locations (5)
CHU de Besançon
Besançon, France
CH de Mulhouse
Mulhouse, France
CHRU de Reims
Reims, France
CHR de Metz
Thionville, France
CHRU de Nancy
Vandœuvre-lès-Nancy, France