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RECRUITING
NCT04741711
NA

AMBulatory UltraSound for Heart Failure Management

Sponsor: Central Hospital, Nancy, France

View on ClinicalTrials.gov

Summary

AMBUSH study is a multicenter randomized, controlled, open-label clinical trial (PROBE (Prospective Randomized Open Blinded End-point) type). The main objective of AMBUSH study is to assess the effect of therapeutic management guided by pulmonary ultrasound and the assessment of the inferior vena cava in patients with heart failure seen in an ambulatory (outpatient) setting on a mixed clinical-biological endpoint (including variations of natriuretic peptides - NtProBNP) at 30 days.

Official title: Impact of Ultrasound-guided Therapeutic Management of Ambulatory Patients With Heart Failure : An Open-label Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

182

Start Date

2023-05-15

Completion Date

2027-06-15

Last Updated

2023-05-17

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

An ultrasound (lung and inferior vena cava) will be performed and the heart failure treatments will be guided by the results of the lung ultrasound and the evaluation of the inferior vena cava.

An ultrasound (lung and inferior vena cava) will be performed and the heart failure treatments will be guided by the results of the lung ultrasound and the evaluation of the inferior vena cava. The choice of congestion treatment modalities to be implemented is left to the investigators' discretion, in accordance with European practice guidelines.

PROCEDURE

Usual care without ultrasound guidance

Usual care (i.e. without ultrasound guidance)

Locations (5)

CHU de Besançon

Besançon, France

CH de Mulhouse

Mulhouse, France

CHRU de Reims

Reims, France

CHR de Metz

Thionville, France

CHRU de Nancy

Vandœuvre-lès-Nancy, France