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Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway
Sponsor: University of Calgary
Summary
Treatment of patients with Hypoxemic respiratory failure (HRF) and Acute Respiratory Distress Syndrome (ARDS) is complex. Therapies that have been shown to save the lives of patients with HRF and ARDS are available but they are not always provided. To reduce practice variation and improve adherence to evidence-informed therapies, the investigators developed the Treatment of Hypoxemic Respiratory Failure and ARDS with Protection, Paralysis, and Proning (TheraPPP) Pathway. The overall objective of TheraPPP Pathway is to improve the quality of care for patients with HRF. Implementation of the pathway across Alberta will test the effectiveness and implementation of the TheraPPP Pathway.
Official title: Identification and Treatment of Hypoxemic Respiratory Failure (HRF) and ARDS With Protection, Paralysis, and Proning: TheraPPP Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
19916
Start Date
2021-04-01
Completion Date
2025-10
Last Updated
2024-06-25
Healthy Volunteers
No
Interventions
TheraPPP
TheraPPP Steps: Step 1. All mechanically ventilated patients will have a height measured and documented. Step 2. Screening for HRF. Step 3. Initiate Lung Protective Ventilation (LPV). Step 4. Paralysis. Step 5. Prone Positioning.
Locations (17)
Peter Lougheed Centre (PLC)
Calgary, Alberta, Canada
Foothills Hospital Intensive Care Unit
Calgary, Alberta, Canada
Foothills Medical Center Cardiovascular ICU
Calgary, Alberta, Canada
Rockyview General Hospital
Calgary, Alberta, Canada
South Health Campus
Calgary, Alberta, Canada
Royal Alexandra Hospital
Edmonton, Alberta, Canada
Misericordia Community Hospital
Edmonton, Alberta, Canada
Mazankowski Alberta Heart Institute
Edmonton, Alberta, Canada
University of Alberta Hospital General Systems ICU
Edmonton, Alberta, Canada
University of Alberta Hospital Neurosciences Intensive Care Unit
Edmonton, Alberta, Canada
Grey Nuns Community Hospital
Edmonton, Alberta, Canada
Northern Lights Regional Health Centre
Fort McMurray, Alberta, Canada
Queen Elizabeth II Hospital
Grande Prairie, Alberta, Canada
Chinook Regional Hospital
Lethbridge, Alberta, Canada
Medicine Hat Regional Hospital
Medicine Hat, Alberta, Canada
Red Deer Regional Hospital Centre
Red Deer, Alberta, Canada
Sturgeon Community Hospital
St. Albert, Alberta, Canada