Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years * Indication for catheter ablation intervention with planned preoperative cardiac CT scan * Prior myocardial infarction (using the international definition of MI: Q waves or imaging evidence of regional myocardial akinesis/thinning in the absence of a non- ischemic cause with documentation of prior ischemic injury) and * One of the following monomorphic VT events within last 6 months: * A: ≥3 episodes of symptomatic VT treated with antitachycardia pacing (ATP), * B: ≥1 appropriate ICD shocks, * C: ≥3 VT episodes within 24 hr * D: sustained VT below detection rate of the ICD documented by ECG or any cardiac monitor * E: Sustained VT recorded on 12 leads ECG in the absence of ICD * Signed informed consent * Affiliated or beneficiary of health insurance Exclusion Criteria: * Unable or unwilling to provide written informed consent. * Active ischemia (acute thrombus diagnosed by coronary angiography, or dynamic ST segment changes demonstrated on ECG) or another reversible cause of VT (e.g. drug-induced arrhythmia), had recent acute coronary syndrome within 30 days thought to be due to acute coronary arterial thrombosis, or have CCS functional class IV angina. Note that biomarker level elevation alone after ventricular arrhythmias does not denote acute coronary syndrome or active ischemia. * Are known to have protruding left ventricular thrombus or mechanical aortic and mitral valves. * Have had a prior catheter ablation procedure for VT * Presenting arrhythmia: polymorphic VT or ventricular fibrillation (VF). * Are in renal failure (Creatinine clearance \<30 mL/min), have NYHA Functional class IV heart failure, or a systemic illness likely to limit survival to \<1 year. * Pregnancy, breast feeding women and women who are of childbearing age and not practicing adequate birth control. (French HAS criteria or following methods are considered adequate): * Combined hormonal contraception * Injected hormonal contraception * Implanted hormonal contraception * Progesterone-only hormonal contraception associated with inhibition of ovulation * Placement of an intrauterine device (IUD) * Placement of intrauterine hormone-realising system (IUS) * Patient under legal protection.