Clinical Research Directory

Inclusion Criteria: \- Women undergoing embryo transfer in either fresh or frozen cycles Exclusion Criteria: * Women aged \> 42 years old * Women with factors which will affect uterine contractility * congenital uterine anomaly * acquired uterine pathology such as myoma \>5cm, adenomyosis \>5cm or endometrial polyp * Women with presence of hydrosalpinx * Women undergoing pre-implantation genetic test in IVF cycles * History of allergy to misoprostol , Buscopan® or same group of drug * Contraindication to the use of Buscopan® e.g. glaucoma, myasthenia gravis, tachycardia, megacolon * Women who are on other smooth muscle relaxant other than Buscopan®