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RECRUITING
NCT04760522
NA

Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program

Sponsor: University Hospital Tuebingen

View on ClinicalTrials.gov

Summary

The GE-MED APPROACH project will enroll patients (n = appr. 12.000) with unclear molecular cause of the disease, suspected genetic cause of the disease without detailed molecular analysis like Whole Exome Sequencing (WES). The novelty of this study is to integrate genomic health concepts into immediate clinical care. To achieve these goals, a novel structure for the Triple P (3P) concept of personalized medicine (Personalized, Predictive, Preventive) integrated into a well-established health care system and associated with novel decentralized Disease Analysing Task Forces (DATF) will be implemented. The overall goal of this study is to implement, for the first time, Whole Genome Sequencing (WGS) analysis as a first line diagnostic test for all clinical indications such as Rare Disease (RD )and familial cancer syndromes.

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

12000

Start Date

2021-06-01

Completion Date

2027-07

Last Updated

2023-11-29

Healthy Volunteers

No

Interventions

GENETIC

WGS Diagnostic: Blood take for genetic diagnostic

Blood sampling, short clinical characterization, WGS based sequencing, NGS analysis and other omics analysis (transcriptomics, proteomics, metabolomics).

Locations (1)

University Hospital Tübingen

Tübingen, Germany