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ACTIVE NOT RECRUITING

NCT04760899

Cerebellar TDCS for SRPCS Treatment

Sponsor: University of Iowa

View on ClinicalTrials.gov

Summary

This study is investigating the immediate and long-term effects of bilateral cerebellar transcranial direct current stimulation on cognition, balance, and symptom severity in people with sports-related post-concussion syndrome. The central hypothesis is that tDCS will provide improvements in cognitive deficits, balance, and overall symptom attenuation in people with SRPCS both acutely and at 2 and 4 week follow ups. The researchers further hypothesize that cerebellar tDCS will ameliorate the symptoms of people with SRPCS.

Official title: Bilateral Cerebellar Transcranial Direct Current Stimulation (tDCS) for the Treatment of Sports-Related Post-Concussion Syndrome (SRPCS)

Key Details

Gender

All

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

Start Date

2021-03-01

Completion Date

2027-07

Last Updated

2025-03-21

Healthy Volunteers

Yes

Conditions

Post-Concussion Syndrome

Interventions

DEVICE

Transcranial Direct Current Stimulation

Transcranial Direct Current Stimulation is a form of non-invasive brain stimulation. It uses small electrodes to deliver small amounts of current to specific areas of the brain to either increase or decrease excitability.

Inclusion Criteria: 1. Sign Informed Consent Document 2. Stated willingness to comply with all study procedures and availability for the duration of the study Male or female, aged 18-30. 3. Diagnosed with a concussion by a doctor greater than or equal to 1 month ago. 4. Concussion occurring during a sport/recreational activity 5. Meet the ICD-10 diagnostic criteria for Post Concussion Syndrome: 1. history of a traumatic brain injury at least a month in the past 2. 3 or more of the following symptoms: headaches, dizziness, fatigue, irritability, insomnia, concentration, memory difficulty 6. Rivermead Post Concussion Questionnaire score of at least 21 at baseline. 7. Comprehension of the protocol, as indicated by an ability to respond to questions about the study after reading the consent form. 8. Healthy enough to complete the protocol based, on information obtained from a clinical exam and past medical history. 9. Able to use and be contacted by telephone 10. Able to speak, read, and understand English, and complete questionnaires in English. Healthy Controls 1. No history of mild traumatic brain injury or diagnosed concussion within the last year. 2. Not suffering from any PCS symptoms related to a brain injury 3. No History of a psychiatric condition (other than mild to moderate anxiety or depression) 4. Currently on no prescribed psychoactive medications 5. Comprehension of the protocol, as indicated by an ability to respond to questions about the study after reading the consent form. 6. Healthy enough to complete the protocol based, on information obtained from a clinical exam and past medical history. 7. Able to use and be contacted by telephone 8. Able to speak, read, and understand English, and complete questionnaires in English Exclusion Criteria: \- 1. History/presence of secondary conditions such as seizure disorders (or on medications known to lower seizure threshold), hydrocephalus, diabetes mellitus, or claustrophobia 2. Currently diagnosed drug and/or alcohol addiction 3. Active Psychosis 4. History of a psychiatric condition (other than mild to moderate anxiety or depression) 5. Currently on no prescribed psychoactive medications 6. Not in any kind of memory improvement program or therapy during study participation. 7\. Pregnancy 8. No known fissures or holes in the skull 9. No metallic objects or implanted devices in the skull

Locations (1)

Thorsten of Rudroff

Iowa City, Iowa, United States