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RECRUITING
NCT04760977

Prehospital Management of Hypotensive Trauma in HEMS

Sponsor: Azienda Usl di Bologna

View on ClinicalTrials.gov

Summary

Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality. Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes. Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies. With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

500

Start Date

2021-05-01

Completion Date

2026-05-01

Last Updated

2024-08-13

Healthy Volunteers

No

Interventions

DRUG

Drugs administration

Antifibrinolytics, analgesics, sedatives, neuromuscular blocking agents

DEVICE

Resuscitative endovascular balloon occlusion of the aorta

Resuscitative technique for exsanguinating traumas

BIOLOGICAL

Blood transfusions

Transfuion of transported blood products for exsanguinating traumas

OTHER

Prehospital management

Stay and play strategy vs scoop and run

DEVICE

Prehospital eFAST

Prehospital thorax/abdomen extended focused assessment sonography for trauma

Locations (16)

Ospedale di Alessandria

Alessandria, Italy

Base HEMS Aosta

Aosta, Italy

Ospedale di Bolzano

Bologna, Italy

Base HEMS Borgo Sesia

Borgosesia, Italy

Base HEMS Cuneo-Levaldigi

Cuneo, Italy

Ospedale Careggi Firenze

Florence, Italy

Ospedale di Siena, Ospedale di Pisa

Grosseto, Italy

Ospedale di Siena, Ospedale di Pisa

Massa, Italy

Ospedale di Padova

Padova, Italy

Pavullo HEMS base

Pavullo nel Frignano, Italy

Pieve di Cadore HEMS base

Pieve di Cadore, Italy

Ospedale di Torino

Torino, Italy

Base HEMS Trento

Trento, Italy

Treviso hospital

Treviso, Italy

Udine FVG

Udine, Italy

Ospedale di Verona Borgo Trento

Verona, Italy