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ACTIVE NOT RECRUITING
NCT04763915
NA

Improving Care After Inherited Cancer Testing

Sponsor: Vanderbilt-Ingram Cancer Center

View on ClinicalTrials.gov

Summary

The IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of genetic test results for individuals with a documented pathogenic/likely pathogenic (P/LP) variant, and FC of family cancer history for individuals with a variant of uncertain significance (VUS) in an inherited cancer gene.

Official title: Improving Care After Inherited Cancer Testing (IMPACT) Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

720

Start Date

2022-08-05

Completion Date

2028-12

Last Updated

2025-09-19

Healthy Volunteers

Yes

Interventions

OTHER

Correlative Studies (Survey)

Administer surveys

OTHER

Correlative Studies (Interview)

In-depth interviews among a subset of participants after the 12-month follow-up survey to either: 1) determine additional resources and tailored message that would be helpful; or 2) assess the adaptive intervention

BEHAVIORAL

GeneSHARE

Access to GeneSHARE, a web-based toolkit which includes interactive and narrative components to enhance FC of genetic test results.

BEHAVIORAL

LivingLabReport

Access to LivingLabReport, a website containing multiple resources including a summary of the patient's genetic test results, condition-specific information, recommended CRM, and information on accessing CRM services.

BEHAVIORAL

Standard-of-care & Adaptive Intervention

Receive standard-of-care from their treating healthcare provider. A subset of individuals will also be asked to test and pilot the adaptive intervention, which will consist of tailored resources to promote CRM and FC, after the 12-month follow-up survey.

OTHER

Access to Education Materials

Receive access to VUS educational materials

Locations (1)

Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, United States