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Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Sponsor: University Hospital, Montpellier
Summary
Cervical cancer is a rare pathology. Recent studies showed that the risk of recurrence is higher for patients treated by coelioscopy in comparison with laparotomy. It could be explained by the spread of circulating tumor cells (CTC) due to tumor mobilization during different steps of the surgery. The primary goal is to evaluate the spread of CTC during surgery on peripheral blood samples. The secondary outcome is to evaluation the disease-free survival at 3 and 5 years postoperatively. 20 patients with early stage cervical (IA1 to IB2) eligible to coelioscopic stadification and laparoscopic surgery will be included.
Official title: Preliminary Descriptive Exploratory Pilot Study Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2022-03-10
Completion Date
2027-12-05
Last Updated
2026-06-22
Healthy Volunteers
No
Conditions
Interventions
Blood samples
Peripheral blood samples at the beginning of surgery, after pneumoperitoneum creation and uterine pedicles coagulation.
Locations (3)
Department of gynaecology, Montpellier University Hospital
Montpellier, France
Institut du Cancer de Montpellier - Val d'Aurelle
Montpellier, France
CHU de Nîmes
Nîmes, France