Clinical Research Directory

Inclusion Criteria: * BMI ≥30 kg/m2 * Desire to lose weight * Agrees to attend outcome visits per protocol * Available for class times * Transportation and ability to attend in-person study visits at baseline (screening), 26, 52, and 78 weeks * Able to stand for weight measurements without assistance * Able to speak and read English * Able to download and use the MyFitnessPal and Fitbit apps daily * Possess smart phone with data and texting plan * Have or willing to create a Gmail address * Able to connect to a video conference call using a smartphone, tablet or computer with a webcam and microphone * Score of at least 4 out of 6 on a validated cognitive screener Exclusion Criteria: * Weight \>380 lb * Weight loss of at least 10 lbs in the month prior to screening * Currently enrolled or enrolled in previous month in a clinical, research, or community program focusing on lifestyle change that could affect weight * Current use of weight loss medication * History of bariatric surgery or planning to have bariatric surgery in the study timeframe * Residing in a nursing home or receiving home health care * Impaired hearing * Significant dementia, drug or alcohol misuse, or unstable psychiatric illness (e.g., schizophrenia, psychosis) * Current treatment for cancer or being treated for cancer (besides basal cell carcinoma or squamous cell) in the last 6 months * Use of insulin, sulfonylureas, or meglitinides due to increased risk for hypoglycemia * Pregnant, breastfeeding, or planning to become pregnant within the study timeframe * Diuretic medication doses higher than hydrochlorothiazide 25 mg daily, furosemide 40 mg daily, torsemide 20 mg daily, bumetanide 1 mg daily, or any use of metolazone; use of potassium-sparing diuretics is acceptable * Chronic kidney disease at stage 4 or 5 * Unstable heart disease in the 6 months prior to screening * Exertional chest pain * History of ascites requiring paracentesis * Pain, fainting or other conditions that prohibit mild/moderate exercise