Clinical Research Directory

Inclusion Criteria: * CIU as defined as frequent urticarial lesions for ≥ 6 weeks * Symptoms not controlled with standard dose antihistamines (loratadine 10mg daily, desloratadine 5mg daily, fexofenadine 180mg daily, cetirizine 10mg daily, or levocetirizine 5mg daily) * Planned initiation of treatment with omalizumab (Xolair) as part of standard of care for antihistamine-refractory urticaria Exclusion Criteria: * Use of immunomodulatory drugs in the past 1 month prior to beginning the study * Use of systemic steroids in the past 1 month prior to beginning the study * Use of omalizumab in the past 3 months prior to beginning the study * Use of any investigational agent in the past 30 days * Untreated intercurrent illness * Severe Asthma * Primary diagnosis of flushing