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Invest-CTO PCI Trial
Sponsor: Haukeland University Hospital
Summary
Following unsuccessful CTO crossing a CTO modification procedure is sometimes performed. CTO PCI registries where plaque modification has been performed in some patients, report this to be safe, and associated with higher success rates at subsequent attempts. It has never been investigated whether a planned investment procedure, with an intention that both the initial and staged completion PCI are of shorter duration, could improve safety and efficacy. The investigators hypothesize that 1. A planned investment procedure in the treatment of CTOs will be associated with improved patient safety 2. A planned investment procedure will be associated with improved cumulative procedure success rates 3. A planned two stage procedure will be associated with improved patient experience
Official title: Invest-CTO: Effectiveness and Safety of a Planned Investment Procedure in High-Risk CTO PCI
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2021-12-08
Completion Date
2026-10
Last Updated
2025-11-21
Healthy Volunteers
No
Interventions
Chronic total occlusion(CTO) percutaneous coronary intervention (PCI)
CTO PCI completed as a two step procedure with an initial planned CTO modification and a completion procedure after 8-12 weeks
Locations (5)
Columbia University Medical Center/ NewYork Presbyterian Hospital
New York, New York, United States
Haukeland University Hospital
Bergen, Bergen, Norway
Golden Jubilee National Hospital
Glasgow, Glasgow, United Kingdom
Bristol Health
Bristol, United Kingdom
St George´s Hospital
London, United Kingdom