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RECRUITING
NCT04791436

Oral and Olfactory Complications of Recovered COVID-19 Patients

Sponsor: University of Giessen

View on ClinicalTrials.gov

Summary

This cohort study aims to investigate the long-standing chemosensory disorders and oral manifestation after recovery of the COVID-19 illness. A correlation between the long-standing symptoms and the COVID-19 severity grade will be very important to understand and clarify the aetiology of these symptoms.

Official title: Oral and Olfactory Complications of Recovered COVID-19 Patients: A Prospective Cohort Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

402

Start Date

2021-05-01

Completion Date

2025-05-28

Last Updated

2024-05-13

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Gustatory and olfactory function test

The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

DIAGNOSTIC_TEST

Molecular assessment of saliva

Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.

Locations (1)

Justus-Liebig University

Giessen, Hesse, Germany