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Sarcopenia and Nutritional Status in a Rehabilitation Setting
Sponsor: Fondazione Don Carlo Gnocchi Onlus
Summary
In this pilot observational study the primary outcome is to assess, in a Respiratory Rehabilitation Unit, if there is an association between sarcopenia, assessed by handgrip strenght and BIA, and a delayed decannulation time in patients who underwent tracheostomy. Secondary outcomes are to assess if there is an association between an increased malnutrition risk (assessed by MUST), a poor nutritional status (assessed by GLIM criteria) and a delayed decannulation time and the gut microbiota composition.
Official title: Observational Pilot Study in Patients Who Underwent Tracheostomy: Sarcopenia Assessment by Handgrip Strenght and BIA. Association to Malnutrion Risk, Nutritional Status, Gut Microbioma and Decannulation Time.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2021-06-09
Completion Date
2025-12-31
Last Updated
2025-08-28
Healthy Volunteers
No
Conditions
Interventions
handgrip strenght
Muscle strenght measured with a handheld dynamometer, at admission (T0) and at decannulation time (T1)
Bioelectrical Impedance Analysis (BIA)
Muscle mass evaluated by Bioelectrical Impedance Analysis (BIA), at admission (T0) and at decannulation time (T1)
MUST
Malnutrition risk assessed by Malnutrition Universal Screening Tool (MUST), at admission (T0) and at decannulation time (T1)
GLIM
Malnutrition diagnosis performed by Global Leadership Initiative on Malnutrition (GLIM) criteria, at admission (T0) and at decannulation time (T1)
Gut microbiota
A fecal sample obtained at admission (T0) and at decannulation time (T1)
Blood Sample
A Blood sample obtained at admission (T0) and at decannulation time (T1)
Anthropometric measures
Measurement of weight and height (assessed only at admission) to calculate the Body Mass Index (BMI), at admission (T0) and at decannulation time (T1)
Locations (1)
Fondazione Don Carlo Gnocchi
Florence, Italy, Italy