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Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Sponsor: University of Pittsburgh
Summary
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies find that this increases the risk for substance use (SU). However, what impact circadian rhythm and sleep disruption either together or independently have on the neuronal circuitry that controls reward and cognition, or if there are interventions that might help to modify these disruptions is unknown. Project 2 (P2) of the CARRS center will test an innovative and mechanistic model of brain circuitry that uses multi-method approaches, takes a developmental perspective, and incorporates key sleep and reward constructs.
Official title: Center for Adolescent Reward, Rhythms and Sleep Project 2
Key Details
Gender
All
Age Range
13 Years - 15 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2021-05-01
Completion Date
2026-06-30
Last Updated
2025-11-12
Healthy Volunteers
Yes
Conditions
Interventions
Increase morning bright light
Participants will wear Re-Timer bright glasses for 30 minutes each morning upon rising
Decrease evening blue light
Participants will wear tinted glasses that block blue wavelength light for 2 hours before bed
Sleep Scheduling
Participants will advance their bedtime by 1.5 hours and regularize their wake time
Monitor sleep, mood, and substance use
Participants will complete smartphone-based sleep, mood, and substance use monitoring
Locations (1)
Western Psychiatric Hospital
Pittsburgh, Pennsylvania, United States