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RECRUITING
NCT04792697
NA

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

Sponsor: University of Pittsburgh

View on ClinicalTrials.gov

Summary

Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies find that this increases the risk for substance use (SU). However, what impact circadian rhythm and sleep disruption either together or independently have on the neuronal circuitry that controls reward and cognition, or if there are interventions that might help to modify these disruptions is unknown. Project 2 (P2) of the CARRS center will test an innovative and mechanistic model of brain circuitry that uses multi-method approaches, takes a developmental perspective, and incorporates key sleep and reward constructs.

Official title: Center for Adolescent Reward, Rhythms and Sleep Project 2

Key Details

Gender

All

Age Range

13 Years - 15 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2021-05-01

Completion Date

2026-06-30

Last Updated

2025-11-12

Healthy Volunteers

Yes

Interventions

OTHER

Increase morning bright light

Participants will wear Re-Timer bright glasses for 30 minutes each morning upon rising

OTHER

Decrease evening blue light

Participants will wear tinted glasses that block blue wavelength light for 2 hours before bed

BEHAVIORAL

Sleep Scheduling

Participants will advance their bedtime by 1.5 hours and regularize their wake time

BEHAVIORAL

Monitor sleep, mood, and substance use

Participants will complete smartphone-based sleep, mood, and substance use monitoring

Locations (1)

Western Psychiatric Hospital

Pittsburgh, Pennsylvania, United States