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Labor Induction in Low-risk Nulliparous Women at 39 Weeks of Gestation to Reduce Cesarean: A Randomized Trial of Induction Versus Expectant Management in France (FRENCH-ARRIVE)
Sponsor: University Hospital, Bordeaux
Summary
The recent ARRIVE trial conducted in United States of America in 2014-2017 demonstrates that elective induction of labor at 39 weeks for nulliparous women did result in a significantly lower frequency of cesarean delivery with no significant differences of adverse perinatal outcomes. But the expected benefits of elective labor induction at 39 weeks have to be confirmed in other settings outside US before considering routine induction of labor for all low-risk nulliparous women at 39 weeks of gestation worldwide.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
4200
Start Date
2021-04-12
Completion Date
2027-06
Last Updated
2025-02-11
Healthy Volunteers
No
Conditions
Interventions
Elective labor induction
Elective labor induction at 39 weeks of gestation
Locations (1)
CHU de Bordeaux
Bordeaux, France