Clinical Research Directory
Browse clinical research sites, groups, and studies.
SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial
Sponsor: Milton S. Hershey Medical Center
Summary
Adults (aged 18-65 years) recently diagnosed with SARS-CoV-2 infection who use a 4-day combined intervention of nasal washes with 1% baby shampoo solution and oral gargles with Listerine Antiseptic® will have a reduced SARS-CoV-2 viral load compared to those using nasal and oral washes with normal saline. This combined intervention should be acceptable, tolerable and safe in this population. To test this, investigators are conducting a trial comparing the efficacy of a number of washes in reducing the oral and nasal SARS-CoV-2 viral load among adults.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
171
Start Date
2021-10-01
Completion Date
2026-05-30
Last Updated
2025-10-28
Healthy Volunteers
No
Conditions
Interventions
Shampoo and saline
Nasal washes with 1% baby shampoo solution and oropharyngeal gargles with saline solution
Saline and Listerine
Nasal washes with buffered saline solution and oropharyngeal gargles with Listerine Antiseptic® solution
Shampoo and Listerine
Nasal washes with 1% baby shampoo solution and oropharyngeal gargles with Listerine Antiseptic® solution
Saline and Saline
Nasal washes with buffered saline solution and oropharyngeal gargles with saline solution
Locations (2)
Penn State Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States
Penn State
State College, Pennsylvania, United States