Clinical Research Directory

Inclusion Criteria: * Men and women ages 25-65y * Lean and overweight (BMI 18.5-40 kg/m2) * No acute, chronic, or debilitating medical conditions * No prescription/non-prescription medications or drugs of abuse * Current non-smoker (tobacco and marijuana) * Persons who fit all the above criteria and are suitable based on a medical history and health habits questionnaire, and additional sleep and health profiling questionnaires may be eligible to participate. Exclusion Criteria: * Persons with any acute, chronic, or debilitating medical condition except pre-hypertension will be excluded. * Persons with any symptoms of acute or active illness (e.g. fever, leukocytosis) will be excluded. * Persons with a history of severe psychiatric illness or psychiatric disorders will be excluded. * Persons with a history of regular night/or rotating shift work in the past year, or who have traveled more than three time zones during the one month prior to the study will be excluded. * Pregnant women, decisionally impaired adults, and prisoners will be excluded.