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Association of Periodontal Inflammation on Immune Response in Wound Healing
Sponsor: University of Nebraska
Summary
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.
Key Details
Gender
All
Age Range
21 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
25
Start Date
2021-09-01
Completion Date
2026-07
Last Updated
2025-12-10
Healthy Volunteers
Yes
Conditions
Interventions
Dental Extraction
Extraction
Locations (1)
University of Nebraska, College of Dentistry
Lincoln, Nebraska, United States