Clinical Research Directory

Inclusion Criteria: * Autistic disorder diagnosis. * Age between 13-30 years. * Male gender. * Participated in clinical trial NCT02677051 Exclusion Criteria: * Those that started or continued taking Avmacol® or similar broccoli extracts since leaving our double-blind study. * Absence of a parent or legal guardian and consent, * Those that can not or will not complete all visits and adherence to study regimen. * Seizure within 2 years of screening, * History of chronic kidney, liver or thyroid disease. * Impaired renal function (serum creatinine\> 1.2 mg/dl). * Impaired hepatic function (\> 2x upper limit of normal). * Impaired thyroid function (TSH outside normal limits). * Current infection or treatment with antibiotics. * Chronic medical disorder (e.g., cardiovascular disease, stroke or diabetes) or major surgery within 3 months prior to enrollment. * Less than 13 years or more than 30 years of age. * Female gender. * A diagnosis of autism spectrum disorder other than autistic disorder, for example, Asperger, PDD-NOS ( Pervasive Developmental Disorder-Not Otherwise Specified) etc.