Clinical Research Directory

Inclusion Criteria: * Patients aged 18 years and older * Karnofsky performance status score of ≥70 * Biopsy-proven oligometastatic cancer to the HN * Biopsy-proven primary HN cancer (either mucosal, nodal, skin) * Patients deemed unsuitable by the treating radiation oncologist for radiation treatment with curative intent owing to advanced age, significant comorbidities, poor performance status, distant metastatic disease. * ≥ 1 site amenable to HN SBRT * Capable of providing informed consent * Required to complete any systemic therapy ≥ 10 days prior to planned start of HN SBRT, with no plans to initiate systemic therapy ≥10 days following completion of HN SBRT. Exclusion Criteria: * History of radiation within the projected treatment field * Contraindications to MR imaging per institutional policy * Patients with connective tissue disorders * History of severe claustrophobia * Pregnant and or breastfeeding females * Having an estimated glomerular filtration rate (GFR) \<40 ml/min/1.73m2