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CTC Quantification During TURBT and PKVBT of Transitional Cell Carcinoma in Purging Fluid and Blood
Sponsor: University Teaching Hospital Hall in Tirol
Summary
Transurethral resection of bladder tumor (TURBT) is usually performed in a piecemeal technique. Tumor fragmentation and cell spilling could be responsible for high recurrence rates. Circulating tumor cells (CTCs) have been shown to be a prognostic predictor in disease progression in transitional cell carcinoma. In the current study the investigators aim to quantify CTCs in purging fluid and blood for recurrent intermediate risk bladder cancer during surgery for two different methods: TURBT and Plasma-kinetic vaporization of bladder tumor (PKVBT). Also correlations for recurrence will be investigated for the two different surgical methods.
Official title: Circulating Tumor Cell (CTC) Quantification During Transurethral Resection (TURBT) and Plasma Kinetic Vaporisation (PKVBT) of Transitional Cell Carcinoma in Purging Fluid and Blood: a Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2021-03-14
Completion Date
2025-10
Last Updated
2024-12-09
Healthy Volunteers
No
Conditions
Interventions
Bipolar transurethral resection of bladder tumor (TURBT)
Standard resection in piecemeal technique with standard bipolar cutting loop. (Storz medical, 27040 GP1)
Bipolar transurethral plasma kinetic vaporization of bladder tumor (PKVBT)
Vaporization of bladder tumor with standard bipolar vaporization electrode. (Storz medical, 27040 NB)
Locations (2)
LKH Hall in Tirol, Department of Urology and Andrology
Hall in Tirol, Austria
LKH Salzburg, Department of Urology and Andrology
Salzburg, Austria