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Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung Cancer
Sponsor: National Taiwan University Hospital
Summary
The investigators aim to identify novel circulating methylated biomarkers for early lung cancer detection as well as to develop new technologies that are clinically applicable with high sensitivity and specificity.
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
OBSERVATIONAL
Enrollment
900
Start Date
2021-03-01
Completion Date
2027-12-31
Last Updated
2024-06-18
Healthy Volunteers
Yes
Conditions
Interventions
Blood-derived DNA methylation detection
Up to 20 ml of blood will be collected from each subject, and the blood specimen will be processed to isolate plasma cell-free DNA and immune-derived cells (circulating T cells). Circulating methylated tumor/immune signature will then be identified.
Locations (1)
National Taiwan University Hospital
Taipei, Taiwan