Clinical Research Directory

Inclusion Criteria: For the patient : * Diagnosed with major neuro-cognitive disorders (DSM V) at all severity stages. * Leaving at home * Assisted by a caregiver, from patient's family or personal environment, assuming most of patient care (spending at least 6 hours per week with the patient) * caregiver available to come with the patient to study visits as planned per protocol * existing agitation since at least one month (according to International Psychogeriatric Association (IPA) criteria) * agitation severity ≥ 2 , based on Clinician Global Impression of Severity (CGI-S) (at least mild severity) * the patient, his/her family member/trusted person , or his /her legal responsible has provided written informed consent to participate in the study * referring physician's oral approval obtained for patient participation in the study * Affiliated to French Healthcare System For the caregiver: * Has provided his/her written informed consent to participate in the study * Ability to understand and speak French properly, ability to complete the questionnaires and assess the patient. * Affiliated to French Healthcare System Exclusion Criteria: For the patient: * Agitation symptoms attributable either to other concomitant prescriptions, or to other psychiatric or evolving somatic diseases. * Patient living in a residential care facility or having an institutionalization project within 6 months * Patient with clinically significant or unstable disease that could affect he/her ability to come for the study visit or complete the evaluations planned as per protocol * Concomitant participation to any other interventional research study * Patient under legal protection. For the caregiver: * Caregiver under legal protection. * Limited internet access or caregiver feeling unable to use it