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ACTIVE NOT RECRUITING
NCT04826991
NA

Wells and Enteric Disease Transmission

Sponsor: Temple University

View on ClinicalTrials.gov

Summary

Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from untreated private wells in the US, but in reality, there are no robust epidemiological data that can be used to estimate cases of GI attributable to these sources. We propose the first randomized controlled trial (RCT) to estimate the burden of GI associated with private well water. We will test if household treatment of private well water by ultraviolet light (UV) vs. sham (inactive UV device) decreases the incidence of GI in children under 5. We will also examine the presence of viral, bacterial, and protozoan pathogens in stool and well water from participants. These data will fill a knowledge gap on sporadic GI associated with federally-unregulated private water supplies in the US.

Official title: Wells and Enteric Disease Transmission - A Randomized Trial of Children Supplied Drinking Water From Private Wells (WET-Trial)

Key Details

Gender

All

Age Range

6 Months - 59 Months

Study Type

INTERVENTIONAL

Enrollment

908

Start Date

2021-07-01

Completion Date

2027-08-31

Last Updated

2026-02-24

Healthy Volunteers

Yes

Interventions

DEVICE

Active UV Device

Active water treatment system

DEVICE

Inactive UV Device

Inactive water treatment system

Locations (1)

Temple University

Philadelphia, Pennsylvania, United States