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Cognition and Motor Learning Post-stroke
Sponsor: University of Southern California
Summary
This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological assessments, and brain imaging techniques to determine the impact of post-stroke cognitive impairment severity on two forms of motor learning (explicit and implicit) and examine the role of the dorsolateral prefrontal cortex in the relationship between cognition and explicit motor learning. Ultimately, this work may lead to the development of a more comprehensive, effective treatment approach to improve walking dysfunction in older adults post-stroke.
Official title: Cognition as a Moderator of Motor Learning Post-stroke
Key Details
Gender
All
Age Range
45 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2023-01-16
Completion Date
2026-12-14
Last Updated
2025-11-04
Healthy Volunteers
No
Conditions
Interventions
Explicit motor learning
Participants will be provided with visual feedback of their right and left step lengths on a screen in front of a treadmill.
Implicit motor learning
Participants will walk on a treadmill that drives their right and left legs to move at two different speeds.
Locations (1)
Center for Health Professions
Los Angeles, California, United States