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RECRUITING
NCT04829071
EARLY_PHASE1

Cognition and Motor Learning Post-stroke

Sponsor: University of Southern California

View on ClinicalTrials.gov

Summary

This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological assessments, and brain imaging techniques to determine the impact of post-stroke cognitive impairment severity on two forms of motor learning (explicit and implicit) and examine the role of the dorsolateral prefrontal cortex in the relationship between cognition and explicit motor learning. Ultimately, this work may lead to the development of a more comprehensive, effective treatment approach to improve walking dysfunction in older adults post-stroke.

Official title: Cognition as a Moderator of Motor Learning Post-stroke

Key Details

Gender

All

Age Range

45 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

65

Start Date

2023-01-16

Completion Date

2026-12-14

Last Updated

2025-11-04

Healthy Volunteers

No

Interventions

BEHAVIORAL

Explicit motor learning

Participants will be provided with visual feedback of their right and left step lengths on a screen in front of a treadmill.

BEHAVIORAL

Implicit motor learning

Participants will walk on a treadmill that drives their right and left legs to move at two different speeds.

Locations (1)

Center for Health Professions

Los Angeles, California, United States