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Sustained Oral Fiber Supplementation for Patients Undergoing Donor Stem Cell Transplantation for Hematological Malignancies
Sponsor: Fred Hutchinson Cancer Center
Summary
This clinical trial examines sustained oral fiber supplementation for patients undergoing donor stem cell transplantation for hematological malignancies. Patients undergoing donor stem cell transplantation often develop oral and gastrointestinal damage from chemotherapy, radiotherapy, or graft-versus-host disease. Oral fiber nutrition support may improve overall nutrition, support a normal gut microbiome (bacteria that live in the gut) and/or improve gut function in patients undergoing stem cell transplants.
Official title: Feasibility of Implementing Sustained Oral Fiber Supplementation for Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Hematological Malignancies
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2022-06-22
Completion Date
2027-12-31
Last Updated
2026-03-12
Healthy Volunteers
No
Interventions
Kate Farms 1.0
Given enteral nutrition via nasoenteric feeding
Standard of Care Nutritional Support
Given standard of care, which may be parenteral nutrition
Survey Administration
Ancillary studies
Dietary Supplement
Receive fiber supplementation orally or enterally
Biospecimen Collection
Undergo collection of blood and stool samples
Electronic Health Record Review
Ancillary studies
Fiber and Dietary Assessments
Ancillary studies
Locations (1)
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States