Clinical Research Directory
Browse clinical research sites, groups, and studies.
Transorbital Ultrasound and Other Markers for Prognosis Prediction After Cardiac Arrest
Sponsor: University Hospital Pilsen
Summary
In sudden cardiac arrest patients with return of spontaneous circulation, brain damage is one of the main determinants of short-term mortality and poor prognosis (CPC 3-5). It is important to properly select group of patients in whom treatment is futile. According to current guidelines, multimodal approach is recommended. Optic nerve sheath diameter measured by ultrasound is non-invasive, fast, low-cost and readily available bed-side method, but evidence for its use as neuroprognostication modality is limited to only few small studies. The aim of this study is to evaluate validity of ONSD as neuroprognostication method at larger cohort of patients, compare it with other established methods and compare ultrasound and CT measurement of ONSD.
Official title: Transorbital Ultrasound and Other Markers for Prognosis Prediction After Cardiac Arrest (TOMCAT)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2021-01-04
Completion Date
2026-12-01
Last Updated
2026-04-09
Healthy Volunteers
No
Conditions
Interventions
Optic nerve sheath diameter measured by transorbital ultrasound
Optic nerve sheath diameter measured 3 mm behind eyeball. For every eyeball 2 measurements in axial and 2 measurements in sagital projections are performed. Summary value for every eyeball is arithmetic mean from these 4 measurements.
Locations (1)
University Hospital Plzen
Pilsen, Czechia