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Cardiac Arrhythmia in Patients with End-Stage Renal Disease
Sponsor: Rigshospitalet, Denmark
Summary
The study will examine the presence of cardiac arrhythmias in patients receiving hemodialysis and the role of diabetes, hypoglycemia and parameters related to uremia and the dialysis procedure. The study is designed as a prospective cohort study with 18 months follow-up. 70 patients receiving chronic hemodialysis will be recruited and equipped with implantable loop recorders (ILR): 35 patients with diabetes and 35 patients without diabetes. Data collection during the follow-up includes continuous monitoring of the heart rhythm by the ILR for the entire follow-up period, continuous glucose monitoring for 10 days every second month, and monthly collection of blood samples and dialytic parameters. After the initial 18-month follow-up, heart rhythm monitoring will continue until the ILR battery runs out for those participants who wish to continue.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2021-06-01
Completion Date
2026-04
Last Updated
2024-11-18
Healthy Volunteers
No
Interventions
Loop recorder (Reveal LINQ, Medtronic)
Implantation of a loop-recorder
Continuous Glucose Measurement (G6, Dexcom)
Monitoring with a continuous glucose monitor
Locations (4)
Department of Nephrology, Rigshospitalet
Copenhagen, Denmark
Department of Nephrology, Herlev Hospital
Herlev, Denmark
Department of Nephrology, North Zealand Hospital
Hillerød, Denmark
Department of Nephrology, Holbæk Sygehus
Holbæk, Denmark