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NOT YET RECRUITING
NCT04845529
NA

Improving Awareness for Spatial Neglect With tDCS

Sponsor: University of Geneva, Switzerland

View on ClinicalTrials.gov

Summary

Brain-damaged patients can show severe neurological and cognitive deficits, and yet often remain strikingly unaware of these symptoms: this condition is called anosognosia. The aim of this study is to improve awareness in right-brain-damaged patients with Unilateral Spatial Neglect (USN) following stroke using transcranial direct current stimulation (tDCS). tDCS is a neuromodulatory technique that delivers low-intensity current to the brain facilitating (anodal tDCS) or inhibiting (cathodal tDCS) spontaneous neuronal activity. tDCS does not induce activity in resting neuronal networks, but modulates spontaneous neuronal activity: consequently, the amount and direction of effects critically depend on the previous state of the neural structures. We will test USN patients showing anosognosia for neglect symptoms. Different brain areas will be stimulated, to target explicit and implicit components of anosognosia, including parietal and frontal brain regions.

Official title: Improving Awareness in Right-brain-damaged Patients With Unilateral Spatial Neglect Using Transcranial Direct Current Stimulation (tDCS)

Key Details

Gender

All

Age Range

20 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2026-12

Completion Date

2027-01

Last Updated

2025-05-30

Healthy Volunteers

No

Interventions

DEVICE

transcranial direct current stimulation (tDCS)

We will apply tDCS to the patients' brains for 20 minutes at the intensity of 1.5mA. Each patient will undergo the three sessions (separated by at least 24h to minimize carry-over effects), in a pseudo-randomized order across patients.