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Randomized Comparison Between Sentinel Lymph Node Biopsy and Lymph Node Dissection in Early Stage Endometrial Cancer
Sponsor: Asan Medical Center
Summary
Through this clinical trial, the investigators aim to verify the usefulness and stability of sentinel lymph node mapping in endometrial cancer of clinical stage I-II.
Official title: Prospective Randomized Comparison of Sentinel Lymph Node Mapping Using Indocyanine Green and Conventional Pelvic Lymph Node Dissection in Clinical Stage I-II Endometrial Cancer
Key Details
Gender
FEMALE
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
810
Start Date
2022-01-26
Completion Date
2029-12-01
Last Updated
2022-02-21
Healthy Volunteers
No
Conditions
Interventions
Sentinel lymph node mapping
Laparoscopic or robotic hysterectomy with/without bilateral salpingo-oophorectomy 2. Inject 1.25 mg/ml of ICG and a total of 6ml into the cornual area (0.5-1 cm deep) of the uterus. And then inject 1 ml of mucous membrane (1-3 mm deep) and 1 ml of substrate (1-2 cm deep) into the cervix, and a total of 4 ml in each direction of 3 and 9 o'clock. 3\. Sentinel lymph node is excised
Routine lymph node dissection
1. Laparoscopic or robotic hysterectomy with/without bilateral salpingo-oophorectomy 2. Lymph node detection is performed.
Locations (1)
Asan Medical Center
Seoul, South Korea