Clinical Research Directory

Inclusion Criteria: Healthy Volunteers * aged 18 to 40 years old and aged 60 to 80 years old * native French speaker * right-handed * with a level of education greater than or equal to the Certificate of Primary Education * free of any medical or psychiatric condition that may interfere with cognition Neurological patients * patients with mild neurocognitive impairment due to Alzheimer's disease * patients with semantic dementia syndrome * right-handed patients with a right or left unilateral surgical lesion of the anterior temporal lobe as a result of pharmaco resistant temporal epilepsy, with no seizures in the last 6 months, with a memory quotient greater than 75, and free of internal extra temporal lesions on MRI * patients with autoimmune limbic encephalitis who have been seizure-free for one month * 1 KA patient, suffering from the rare syndrome of developmental amnesia Exclusion Criteria: All participants * MRI contraindications * sensory deficit interfering with experimental tests * protected major (safeguard justice, trusteeship and guardianship) and persons deprived of liberty Healthy volunteers \- deficit score on the MoCA scale according to current calibrations Neurologic patients * 7-items modified Hachinski ischemic score \>2 * dementia * epileptic seizure in the month prior to inclusion for epileptic patients undergoing surgery and limbic encephalitis patients