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Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Sponsor: Odense University Hospital
Summary
Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health costs. With this protocol, we want to elucidate alternative treatment methods for especially recurrent urinary tract infection. Bacteria have internal competitiveness (bacterial interference) and it is known that the non-pathogenic E.coli can outcompete the pathogenic E.coli in laboratory studies. We intend to strengthen the clinical evidence that it can be used as patient treatment through a clinical, placebo-controlled, double-blind trial at Odense University Hospital.
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-01-09
Completion Date
2027-12-01
Last Updated
2025-09-18
Healthy Volunteers
Yes
Conditions
Interventions
ABU bladder lavage
Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with the non-pathogenic bacterial strain (ABU)
Saline bladder lavage
Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with saline
Locations (2)
Aarhus University Hospital
Aarhus N, Denmark
Odense University Hospital
Odense C, Denmark