Clinical Research Directory

Inclusion Criteria: 1. Subject agrees to consent to the study by signing the Independent Review Board (IRB) approved ICF. 2. Subject is eighteen (18) years old or older. 3. Subject is willing and able to attend all study follow-up visits for up to one (1) year postoperatively (as defined in the study protocol and ICF). 4. Subject can read, understand, and communicate responses to Patient Reported Outcome Measures (PROMs). 5. Subject is suitable for the CORI™ Surgical System. 6. Subject requires a cemented TKA as a primary indication due to any of the following conditions: * Degenerative joint disease, including osteoarthritis * Rheumatoid arthritis. * Avascular necrosis. * Requires correction of functional deformity * Requires treatment of fractures that were unmanageable using other techniques. Exclusion Criteria: 1. Contraindications or hypersensitivity to the use of the CORI™ Surgical System per the IFU. 2. Participation in the treatment period of another clinical trial within thirty (30) days of the Pre-Operative Visit, or during the study. 3. Women who are pregnant, nursing, or of child-bearing potential who are not utilizing birth control measures. 4. Subjects who are non-English speaking. 5. Any subject that meets the definition of a Vulnerable Subject per ISO 14155. 6. Subjects who have participated previously in this clinical trial 7. Subjects with a history of poor compliance with medical treatment. 8. Subject needs a CORI™ Surgical System TKA on the index joint as a revision for a previously failed surgery, or need for complex implants, or any other implant than a standard TKA (e.g., stems, augments, or custom-made devices). 9. Subject has been diagnosed with post-traumatic arthritis 10. Subject needs a bilateral TKA. 11. Subject has active infection or sepsis (treated or untreated) 12. Subject is morbidly obese with a body mass index (BMI) greater than 40. 13. Subjects with a medical or physical condition that, in the opinion of the Investigator, would preclude safe subject participation in the study. This includes: * Advanced osteoarthritis * Joint disease * Paget's or Charcot's disease * Vascular insufficiency * Muscular atrophy * Uncontrolled diabetes * Moderate to severe renal insufficiency * Neuromuscular disease * Mental illness or mental retardation * Drug or alcohol abuse