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Detection of Alzheimer's Disease (AD)-Related Seeds for AD Diagnosis
Sponsor: Capital Medical University
Summary
The study will investigate the biomarkers of Aβ and Tau seeds in plasma detected by Alzheimer's disease (AD) related seeds quantitative detector (AD-seeds-detector), and their sensitivity and specificity in diagnosing AD, compared with those from age-matched cognitively normal controls, and those with other types of dementia. To perform a high throughput analysis of the amount of Aβ and Tau seeds, the investigators have developed an AD-seeds-detector, in which a fluorescence microplate reader was combined with an oscillating mixer or water-bath-type ultrasonicator.
Official title: Detection of Alzheimer's Disease (AD)-Related Seeds as Biomarkers for Accurate Diagnosis of AD（AD-seeds-detector）
Key Details
Gender
All
Age Range
55 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
1500
Start Date
2020-08-26
Completion Date
2026-12-31
Last Updated
2026-03-23
Healthy Volunteers
Yes
Conditions
Locations (1)
Xuanwu Hospital of Capital Medical University
Beijing, Beijing Municipality, China