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RECRUITING
NCT04850105

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Sponsor: Akcea Therapeutics

View on ClinicalTrials.gov

Summary

This is a prospective, non-interventional, Long-term, multinational cohort safety study of patients with Hereditary Transthyretin Amyloidosis with Polyneuropathy (hATTR-PN). The overarching goal of this study is to further characterize the long-term safety of TEGSEDI (inotersen) in patients with hATTR-PN under real-world conditions.

Official title: A Prospective, Non-interventional, Long-term, Multinational Cohort Safety Study of Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (hATTR-PN)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

240

Start Date

2021-09-21

Completion Date

2036-03-31

Last Updated

2025-09-11

Healthy Volunteers

No

Interventions

OTHER

Data Collection

Data on each patient will be collected at study enrollment and at each follow-up visit. No mandatory visits, tests, or assessments are required for this study. All visits will be scheduled and conducted according to the clinical site's normal clinical practice.

Locations (26)

Study Centre

Sofia, Bulgaria

Study Centre

Égkomi, Nicosia, Cyprus

Study Center

Lille, Cedex, France

Study Center

Nice, Romaine, France

Study Centre

Nantes, France

Study Center

Heidelberg, Germany

Study Center

Athens, Greece

Study Center

Athens, Greece

Study Center

Heraklion, Greece

Study Centre

Roma, Rome, Italy

Study Center

Bologna, Italy

Study Center

Genova, Italy

Study Center

Messina, Italy

Study Center

Milan, Italy

Study Center

Naples, Italy

Study Center

Pavia, Italy

Study Center

Roma, Italy

Study Center

Roma, Italy

Study Center

Lisbon, Portugal

Study Center

Huelva, Andalusia, Spain

Study Centre

Oviedo, Avenida de Roma, Spain

Study Center

Palma de Mallorca, Balearic Islands, Spain

Study Centre

Villarreal, Barcelona, Spain

Study Centre

Barcelona, Catalonia, Spain

Study Centre

Madrid, Madrid, Spain

Study Center

Madrid, Spain