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RECRUITING
NCT04852588
NA

Chest Lymph Node Sampling in Patients With Advanced Lung Cancer to be Treated With Curative-intent Radiation Treatment

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

View on ClinicalTrials.gov

Summary

This study will investigate the role of sampling suspicious chest lymph nodes with a procedure called endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TFNA) or transesophageal ultrasound-guided fine needle aspiration (EUS-FNA) in patients planned to receive radical dose radiation. This study will use Stereotactic Ablative Radiotherapy (SABR) for treatment methods. SABR is a newer radiation treatment that delivers high-dose, precise radiation to small tumors and can be delivered more accurately than with older radiation treatment methods. It is considered a standard treatment for small lung cancers, and select cancers that have spread to the brain. The purpose of this study is to compare if the lymph node sampling procedure is valuable for determining the extend of nodal disease in metastatic Non-Small Cell Lung Cancer (NSCLC) compared to imaging alone.

Official title: Endoscopic Nodal Staging in Oligometastatic Non-small Cell Lung Cancer (NSCLC) Being Treated With Stereotactic Ablative Radiotherapy (ENDO-SABR)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

29

Start Date

2021-11-09

Completion Date

2025-05-31

Last Updated

2025-03-28

Healthy Volunteers

No

Interventions

PROCEDURE

Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TFNA)

Chest lymph node sampling procedure by EBUS

PROCEDURE

Transesophageal ultrasound-guided fine needle aspiration (EUS-FNA)

Chest lymph node sampling procedure by EUS

Locations (2)

London Health Sciences Centre - London Regional Cancer Program

London, Ontario, Canada

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada