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THC + CBD and Memory Study
Sponsor: Hartford Hospital
Summary
Memory deficits are one of the most consistently observed cognitive effects of marijuana use. There is evidence that some decrements attributable to the primary psychoactive ingredient, delta-9-tetrahydrocannabinol (THC), may be attenuated by cannabidiol (CBD). This study will help us learn more about the relationship between THC and CBD consumption with memory processes. A combination of MRI and neuropsychological tests (which are computer and paper/pencil tasks) will be used to measure the neurocognitive and behavioral impacts of THC and CBD use.
Official title: Effects of Marijuana on Memory-Related Neurochemistry and Neural Response
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
9
Start Date
2025-12-01
Completion Date
2026-12-30
Last Updated
2025-03-17
Healthy Volunteers
Yes
Interventions
High THC/No CBD Marihuana
high THC (65 mg THC) and no CBD (0 mg CBD)
High THC/High CBD Marihuana
high THC (65 mg THC) and high CBD (50 mg CBD)
No THC/No CBD Marihuana
no THC (0 mg THC) and no CBD (0 mg CBD); placebo drug