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Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection
Sponsor: Vir Biotechnology, Inc.
Summary
This is a phase 2 study in which participants with chronic hepatitis B virus (HBV) infection will receive VIR-2218, VIR-3434 and/or PEG-IFNα and be assessed for safety, tolerability, and efficacy
Official title: A Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of Regimens Containing VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
244
Start Date
2021-07-11
Completion Date
2026-03
Last Updated
2025-10-21
Healthy Volunteers
No
Conditions
Interventions
VIR-2218
VIR-2218 given by subcutaneous injection
VIR-3434
VIR-3434 given by subcutaneous injection
PEG-IFNα
PEG-IFNα given by subcutaneous injection
Locations (37)
Investigative Site
San Francisco, California, United States
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Miami, Florida, United States
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Orlando, Florida, United States
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Baltimore, Maryland, United States
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Hillsborough, New Jersey, United States
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Toronto, Canada
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Toronto, Canada
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Vancouver, Canada
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Frankfurt, Germany
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Hanover, Germany
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Mannheim, Germany
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Hong Kong, Shatin, Hong Kong
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Hong Kong, Tai Po District, Hong Kong
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Hong Kong, Hong Kong
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Kuala Lumpur, Malaysia
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Chisinau, Moldova
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Auckland, New Zealand
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Auckland, New Zealand
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Hamilton, New Zealand
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Tauranga, New Zealand
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Wellington, New Zealand
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Bucharest, Romania
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Busan, South Korea
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Seoul, South Korea
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Seoul, South Korea
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Yangsan, South Korea
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Chiayi City, Taiwan
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Kaohsiung City, Taiwan
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Kaohsiung City, Taiwan
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Taichung, Taiwan
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Taipei, Taiwan
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Taoyuan, Taiwan
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Kyiv, Ukraine
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Birmingham, United Kingdom
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London, United Kingdom
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London, United Kingdom
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Manchester, United Kingdom