Clinical Research Directory

Inclusion Criteria: * Adult patients presenting Barrett's esophagus of a size between 2 cm and 6 cm in the height of the longest tonguea with low to high grade dysplasia that is histologically proven or with a superficial non-invasive adenocarcinoma that has been resected a The total height of the BE is evaluated according to the Prague classification, with the height of the circumferential segment between 0 cm (non-circumferential segment) and 6 cm (segment shaped like a full sleeve for 6 cm), referred to as C0 to C6, and the height of the longest tongue between 2 cm and 6 cm (M2- M6). * Patients must have signed the consent form in order to participate in the study * Patients are pre-included (signature of consent) before the histological confirmation of dysplasiab and/or superficial non-invasive adenocarcinoma that allows the patient to be included in the study. Exclusion Criteria: * Individuals over 85 years old * Women who are pregnant, breastfeeding or in labour * Individuals in detention through judicial or administrative decision * Individuals who are the subject of psychiatric treatment under duress * Individuals who are subjects of legal protection measures * Individuals who are in no state to give their consent * Individuals who do not understand French or do not know how to read * Individuals who are not part of a social security program or benefit from such a scheme * Those with active peptic and/or radiation-induced or complicated esophagitis at the time of treatment * Presence of a visible lesion that is suspected to be esophageal cancer confirmed by biopsies * Anterior resection of invasive adenocarcinoma using endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) with invasion of the lateral and/or deep margin, adenocarcinoma of poorly differentiated characteristics or sub-mucosal invasion \> 500µm (pT1b) * All preliminary ablation treatments or dilation for esophageal stenosis * Significant esophageal stenosis: cannot be passed with a standard gastroscope * Presence of esophageal varices or portal hypertension * Anticoagulant treatment that cannot be stopped before the intervention (excluding 100 mg maximum per day of aspirin in single-drug treatment) or any haemostasis problems that cannot be corrected * Having a contraindication regarding anaesthesia * Patients incapable of taking proton pump inhibitors (PPIs) orally.